Updated: Aug 18, 2026
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| Certification Vendor: | Association of Clinical Research Professionals (ACRP) |
| Exam Name: | ACRP Certified Professional Exam |
| Exam Number: | ACRP-CP |
| Exam Format: | Multiple-choice questions, Recall questions, Scenario-based questions |
| Related Certifications: | ACRP Certified Clinical Research Associate (CCRA) ACRP Certified Clinical Research Coordinator (CCRC) ACRP Certified Principal Investigator (CPI) |
| Exam Price: | $435 – $600 |
| Real Exam Qty: | 125 (100 scored, 25 pre-test) |
| Passing Score: | Scaled score of 600 or higher |
| Available Languages: | English |
| Certificate Validity Period: | 3 years |
| Exam Duration: | 180 minutes |
| Recommended Training: | ACRP Official Training Resources |
| Exam Registration: | ACRP Official Registration |
| Sample Questions: | ACRP ACRP-CP Sample Questions |
| Exam Way: | Online remote proctored or in-person at PSI test centers |
| Pre Condition: | 3,000 hours verifiable clinical research work experience; or 1,500 hours plus clinical research degree |
| Official Syllabus URL: | https://acrpnet.org/certification/acrp-cp-certification |
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Professionalism and Ethical Practice | 15% | - Professional standards
|
| Topic 2: Clinical Study Operations | 15% | - Site management
|
| Topic 3: Data Management and Informatics | 17% | - Data collection
|
| Topic 4: Study Design and Conduct | 17% | - Study planning
|
| Topic 5: Ethical and Participant Safety Considerations | 19% | - Clinical care and management of research participants
|
| Topic 6: Regulatory and Compliance Requirements | 17% | - ICH Guidelines
|
1. A sponsor writes a protocol comparing an IP XYZ to a marketed drug ABC to determine if XYZ is more efficacious in the target population than ABC. Both drugs are prepared in identically masked IV bags and distributed according to the randomization scheme outlined in the protocol such that the study team is unaware of the treatment assignment.
Which of the following is an appropriate title for this study?
A) A randomized, double-blind, double-dummy, superiority study comparing the efficacy of XYZ to ABC in the target population
B) A randomized, open-label, comparator study comparing the efficacy of XYZ to ABC in the target population
C) A randomized, double-blind, superiority study comparing the efficacy of XYZ to ABC in the target population
D) A randomized, single-blind, placebo-controlled study comparing the efficacy of XYZ to ABC in the target population
2. A study protocol must contain which of the following elements?
A) Data management plan
B) Chemical structure of the IP
C) Description of statistical methods
D) Participant reimbursement details
3. A clinical trial is conducted to measure the effectiveness of music therapy to reduce anxiety in intensive care unit patients. Patients are randomly assigned to receive headphones with music of their choice or headphones with white noise. The group receiving the white noise headphones is considered which type of control group?
A) Placebo
B) Active control
C) Alternate dose
D) No treatment
4. Which of the following activities is the MOST efficient way of overseeing a CRO's management during a clinical trial?
A) Pre-qualification assessment of CRO
B) Co-monitoring of CRO site visits
C) Central monitoring of data fields by sponsor
D) Risk-based audits of CRO activities as delegated
5. Which of the following elements of the Informed Consent are NOT required?
A) A description of potential benefits
B) Statement that study involves research
C) A description of any reasonably foreseeable risks or discomforts
D) Subject legal rights can be waived
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: C | Question # 3 Answer: A | Question # 4 Answer: D | Question # 5 Answer: D |
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